The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity
Lantibiotics are ribosomally synthesized (methyl)lanthionine containing peptides which can efficiently inhibit the growth of Gram-positive bacteria.As lantibiotics kill bacteria efficiently and resistance to them is difficult to be obtained, they have the potential to be used in many applications, e.g.in pharmaceutical industry or food industry.Nis